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Electrophysiological Analysis of hiPSC-Derived Cardiomyocytes Using a Patch-Clamp Technique

Yuta Yamamoto1,2, Sayako Hirose2, Yimin Wuriyanghai2

  • 1Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center, Suita, Japan.

Methods in Molecular Biology (Clifton, N.J.)
|July 24, 2021
PubMed

Keywords:
Action potential recordingElectrophysiologyHuman-induced pluripotent stem cell-derived cardiomyocytePatch-clamp techniqueVoltage clamp

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Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
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