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Oncogenic activity and cellular functionality of melanoma associated antigen A3

Paula Schäfer1, Themistoklis Paraschiakos1, Sabine Windhorst1

  • 1Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg 20246, Germany.

Biochemical Pharmacology
|July 25, 2021
PubMed
Summary

Melanoma associated antigen A3 (MAGE-A3) is a promising cancer target due to its tumor-specific expression. Despite early trial success, MAGE-A3 immunotherapies require further optimization for clinical efficacy.

Keywords:
Cancer germline antigensCancer vaccineImmunotherapyIntracellular mechanismMAGE-A3Melanoma Associated Antigen A3

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