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Optimization of ultrasound-assisted extraction of polyphenols from globe artichoke (Cynara scolymus L.) bracts
Miguel Angel Quispe1, José Alberto Pacheco Valenzuela2, Alex Rubén Huamán de la Cruz3
1Universidad Nacional del Centro del Perú, El Tambo - Huancayo, Perú.
Background:
The globe artichoke (Cynara scolymus L.) is a rich source of phenolic compounds which may be extracted by ultrasound technology and used as a medicinal alternative. The objective of this work was to determine the radiation amplitude (%), ethanol concentration (%), and time extraction (min) required to guarantee an elevated content of polyphenol compounds.
Methods:
The optimal extraction conditions were assessed through the Box-Wilson design and by applying Composite Face Centered (CCFC) and total phenolic compounds (TPC) as the response variables.
Results:
A quadratic model was adequate, with R2 = 0.993. The optimal conditions were a radiation amplitude of 97%, an ethanol concentration of 53%, and an extraction time of 9.7 min. The optimized extract of artichoke bracts (Cynara scolymus L.) showed a TPC of 25.13 (±0.030) mg GAE/g, an antioxidant activity DPPH of 39.79 (±0.014) mmol Trolox equivalents (TE), and an antioxidant capacity TEAC of 33.98 (±0.03) mmol Trolox equivalents.
Conclusions:
The results showed values closely related to the expected values, indicating that the models were well-developed.
