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A serial study of changes in intrathecal immunoglobulin synthesis in a patient with central nervous system systemic
1Department of Medicine, Central Hospital of Japanese National Railways, Tokyo.
The Journal of Rheumatology
|October 1, 1987
Abstract:
A 50-year-old man with systemic lupus erythematosus developed organic brain syndrome. He responded to corticosteroid therapy and recovered completely from acalculia, apraxia and memory disturbance. Throughout his course, the cerebrospinal fluid (CSF) IgM, IgA and IgG indices were decreased in relation to the progression of normal alpha activity in the electroencephalogram. CSF Ig indices may be useful for monitoring central nervous system lupus disease activity.