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Author Spotlight: Leptospira DNA Detection in Water for Environmental Analysis and Disease Surveillance
Published on: June 14, 2024
Ocular leptospirosis in four patients: A diagnostic dilemma
H R Ng1, M Y Cheong2, M Mustapha3
1Hospital Raja Permaisuri Bainun, Department of Ophthalmology, Jalan Hospital, 30250 Ipoh, Perak, Malaysia. huiruan.ng@gmail.com.
Abstract:
Leptospirosis is a zoonotic disease that is caused by the pathogenic spirochetes of the genus Leptospira. The infection occurs worldwide and is particularly more common in the tropics. However, it is becoming a neglected reemerging global health disease due to rapid urbanisation. This disease has a wide range of clinical manifestations from flu-like illness to pneumonia, acute kidney injury, etc. But many uncommon clinical findings are being reported as well. In this paper, we report four patients who presented initially with uveitic features who turned out serologically positive for Leptospira after extensive investigations.
Insights
Leptospirosis, a zoonotic disease, can present with unusual symptoms like uveitis. This study identified four patients with uveitis who were later diagnosed with Leptospira infection.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Public Health
Background:
- Leptospirosis is a global zoonotic disease caused by Leptospira spirochetes, prevalent in tropics and reemerging due to urbanization.
- Clinical manifestations range widely from flu-like symptoms to severe organ damage, with uncommon presentations increasingly reported.

