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A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
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Extended Stochastic Gradient MCMC for Large-Scale Bayesian Variable Selection
Qifan Song1, Yan Sun1, Mao Ye1
1Department of Statistics, Purdue University, West lafayette, IN 47906, USA.
Abstract:
Stochastic gradient Markov chain Monte Carlo (MCMC) algorithms have received much attention in Bayesian computing for big data problems, but they are only applicable to a small class of problems for which the parameter space has a fixed dimension and the log-posterior density is differentiable with respect to the parameters. This paper proposes an extended stochastic gradient MCMC algorithm which, by introducing appropriate latent variables, can be applied to more general large-scale Bayesian computing problems, such as those involving dimension jumping and missing data. Numerical studies show that the proposed algorithm is highly scalable and much more efficient than traditional MCMC algorithms. The proposed algorithms have much alleviated the pain of Bayesian methods in big data computing.
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