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Updated: Oct 26, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter ablation of complex cardiac arrhythmias: Single-centre experience in Armed Forces
Pradeep Kumar Hasija1, Prashant Bhardwaj2, Anup Banerji3
1MG Med, HQ Dakshin Bharat Area, India.
Insights
Radiofrequency ablation for complex arrhythmias shows comparable success rates to standard procedures. However, complex ablations involve more hardware, a higher risk of complications, and increased fluoroscopy time.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Complex arrhythmia ablation presents significant technical challenges.
- Advances in mapping and hardware aim to improve outcomes.
- This study analyzes the efficacy of radiofrequency ablation for complex arrhythmias at a tertiary center.
Purpose of the Study:
- To evaluate the efficacy of radiofrequency ablation for complex arrhythmias.
- To compare outcomes of complex ablation procedures with standard procedures.
- To identify associated risks and resource utilization in complex ablations.
Main Methods:
- Retrospective analysis of catheter ablations performed between August 2012 and November 2016.
- Procedures classified as complex if involving 3D electro-anatomical (EA) mapping, special hardware, or trans-septal puncture.
- Standard ablation used conventional catheters with conventional access routes.
Main Results:
- Overall success rates for complex ablations were comparable to standard procedures (87.2% vs. 88.3% after first procedure; 90.4% vs. 94.7% after redo).
- Complex procedures utilized 3D EA mapping (31%), trans-septal puncture (40%), and special hardware (100%).
- Complications (pericardial perforation, cardioembolism) occurred in the complex group; fluoroscopy time was longer (25.10 min vs. 15.23 min).
Conclusions:
- Complex electrophysiological procedures for arrhythmia ablation achieve success rates similar to standard procedures.
- These complex procedures necessitate increased hardware, carry a higher risk of complications, and require longer fluoroscopy times.
- Despite challenges, complex ablation remains a viable option for challenging arrhythmias.
Background:
Complex arrhythmia ablation remains a technical challenge despite advances in hardware and mapping techniques. The aim of the study was to analyse the efficacy of radiofrequency ablation of arrhythmias requiring complex electrophysiological procedures at a tertiary-care centre.
Methods:
A retrospective study was done for catheter ablation of arrhythmias performed at a single centre from Aug 2012 to Nov 2016 (4 years 4 months). The standard ablation involved conventional catheters with antegrade right heart and retrograde left heart access. The procedure was considered complex, if it involved 3 D electro-anatomical (EA) guidance for mapping or required special hardware and/or trans-septal puncture.
Results:
Of 333 electrophysiology (EP) cases 265 qualified for ablation. The cohort of arrhythmias requiring complex procedure (n = 94) comprised of supraventricular 15 (15.9%), atrioventricular 43 (44.7%) and ventricular 36 (38.3%). The procedure used three-dimensional EA mapping in 31; trans-septal puncture for left atrial access in 40; and use of special catheters and sheaths in all 94 procedures. The overall success in the complex group after the first procedure was 87.2% versus 88.3% (P < 0.05), and after redo procedure it was 90.4% vs 94.7% (P < 0.05). There were three complications (pericardial perforation: 2; cardioembolism: 1) only in the complex group. The fluoroscopy time for complex was longer than that of the standard procedure (25.10 ± 6.32 versus 15.23 ± 5.33 min, P = 2.54).
Conclusion:
Arrhythmias requiring complex electrophysiological procedure for ablation have a comparable success rate to standard ablation procedure but at the cost of extra hardware, complications and fluoroscopy time.
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