Related Experiment Video
Updated: Oct 26, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
Published on: October 20, 2023
Benzodiazepine Misuse: An Epidemic Within a Pandemic
Ashish Sarangi1, Terry McMahon1, Jayasudha Gude2
1Psychiatry, Texas Tech University Health Sciences Center, Lubbock, USA.
Benzodiazepine use fluctuated during the COVID-19 pandemic, with some regions seeing increased consumption and others decreased prescription refills. Mental health professionals should exercise caution due to these changing patterns.
Area of Science:
- Psychiatry
- Pharmacology
- Public Health
Background:
- The COVID-19 pandemic exacerbated mental health issues, leading to increased rates of depression, anxiety, and insomnia.
- Benzodiazepines are frequently prescribed for anxiety and insomnia but are also subject to misuse and abuse.
- Pandemic-related measures like lockdowns and social distancing negatively impacted individuals with pre-existing mental health conditions.
Purpose of the Study:
- To assess the extent of benzodiazepine use during the COVID-19 pandemic.
- To interpret the potential future effects of observed benzodiazepine usage trends.
- To identify fluctuations in benzodiazepine consumption patterns globally.
Main Methods:
- A literature search was conducted adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol.
- Eight selected articles were reviewed to analyze benzodiazepine usage during the pandemic.
- Data on benzodiazepine prescription refills and consumption were synthesized.
Main Results:
- Worrying fluctuations in benzodiazepine use were reported across various global regions during the pandemic.
- Some studies indicated an increase in benzodiazepine consumption.
- Other studies observed a decrease in prescription refills, potentially due to disruptions in mental healthcare access.
Conclusions:
- Current trends in benzodiazepine use during the pandemic are characterized by significant fluctuations.
- Mental health professionals must maintain caution when prescribing benzodiazepines amidst these changing patterns.
- Further research is essential to understand evolving usage patterns and prevent widespread misuse or abuse.
Related Concept Videos
CNS Depressants: Barbiturates and Benzodiazepines
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
Anxiolytic Drugs: Benzodiazepines and Buspirone
Sedatives and Hypnotics Drugs: Barbiturates
Sedatives and Hypnotics: Overview
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Management of Insomnia

