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Brugada syndrome associated with out-of-hospital cardiac arrest: A case report
Guo-Hua Ni1, Hua Jiang2, Li Men3
1Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Chengdu Jinjiang Sohome Comprehensive Outpatient Clinic), Chengdu 610072, Sichuan Province, China.
Insights
Brugada syndrome (BrS) is an inherited heart condition that can cause sudden cardiac death. Early recognition of the Brugada ECG pattern is crucial for saving lives.
Area of Science:
- Cardiology
- Genetics
- Electrocardiography
Background:
- Brugada syndrome (BrS) is an inherited cardiac condition.
- It is characterized by a specific ECG pattern (coved-type ST-segment elevation in V1-V3).
- BrS predisposes individuals to sudden cardiac death (SCD) due to ventricular arrhythmias.
Observation:
- A 29-year-old male experienced out-of-hospital cardiac arrest.
- His post-resuscitation ECG showed a type 1 Brugada pattern (coved ST elevation in V1-V2).
- His brother exhibited a type 2 Brugada pattern on ECG.
Findings:
- The patient was diagnosed with BrS, NYHA Class IV heart failure, multiple organ dysfunction syndrome, sepsis, and hypoxic ischemic encephalopathy.
- He remained free of arrhythmia episodes during a 36-month follow-up period post-discharge.
Implications:
- Increased awareness and prompt recognition of the Brugada ECG pattern are vital.
- Early diagnosis and management of BrS can be lifesaving.
- This case highlights the importance of ECG interpretation in patients with cardiac arrest.
Background:
Brugada syndrome (BrS) is an inherited disease characterized by an electrocardiogram (ECG) with a coved-type ST-segment elevation in the right precordial leads (V1-V3), which predisposes to sudden cardiac death (SCD) due to polymorphic ventricular tachycardia or ventricular fibrillation in the absence of structural heart disease. We report the case of a 29-year-old man with out-of-hospital cardiac arrest. BrS is associated with a high incidence of SCD in adults, and increasing the awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
Case Summary:
A 29-year-old man suffered from out-of-hospital cardiac arrest, and after defibrillation, his ECG demonstrated a coved-type elevated ST segment in V1 and V2. These findings were compatible with type 1 Brugada pattern, and ECG of his brother showed a type 2 Brugada pattern. The diagnosis was BrS, NYHF IV, multiple organ dysfunction syndrome, sepsis, and hypoxic ischemic encephalopathy. The patient had no arrhythmia episodes after discharge throughout a follow-up period of 36 mo.
Conclusion:
Increasing awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
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