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Related Experiment Videos

One-quadrant argon laser trabeculoplasty and its indication.

Y Takenaka1, T Yamamoto, S Shirato

  • 1Department of Ophthalmology, Tokyo University School of Medicine, Japan.

Japanese Journal of Ophthalmology
|January 1, 1987
PubMed
Summary

Argon laser trabeculoplasty (ALT) effectively lowered intraocular pressure in open-angle glaucoma patients unresponsive to medication. One-quadrant ALT demonstrated comparable efficacy to standard 180-degree ALT with fewer complications.

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Laser Therapy

Background:

  • Open-angle glaucoma (OAG) management often requires aggressive treatment when medications fail.
  • Intraocular pressure (IOP) control is crucial to prevent glaucomatous optic neuropathy.
  • Argon laser trabeculoplasty (ALT) is an established procedure for lowering IOP.

Purpose of the Study:

  • To evaluate the efficacy and safety of one-quadrant Argon laser trabeculoplasty (ALT) in patients with open-angle glaucoma.
  • To compare the outcomes of one-quadrant ALT with standard 180-degree ALT.
  • To assess the long-term IOP control achieved with ALT.

Main Methods:

  • Seventy-one eyes of 55 patients with medically uncontrolled open-angle glaucoma underwent ALT.
  • The procedure involved 25 burn spots applied to the inferotemporal quadrant.

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  • A subset of 18 eyes received a second treatment in the inferonasal quadrant.
  • Success was defined as postoperative IOP below 20 mmHg with continued medication.
  • Life-table analysis was used to determine the success rate over time.

    • Main Results:

    • The overall success rate for IOP control below 20 mmHg was 68% +/- 8% at 15 months.
    • One-quadrant ALT achieved comparable IOP control to standard 180-degree ALT.
    • Fewer complications were observed with the one-quadrant ALT approach compared to the standard procedure.

    Conclusions:

    • One-quadrant Argon laser trabeculoplasty is an effective treatment for open-angle glaucoma when medication is insufficient.
    • This modified ALT approach offers similar IOP-lowering efficacy to the standard procedure but with an improved safety profile.
    • ALT remains a valuable therapeutic option for managing refractory open-angle glaucoma.