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Updated: Oct 26, 2025

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Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
Published on: November 16, 2015
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[Palatine tonsil lymphoma: a pediatric case report]
Roxana Spini1, Daniel Cruz2, Lucía Fernández3
1División de Otorrinolaringología, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires, Argentina. roxanaspini@intramed.net.
Archivos Argentinos De Pediatria
|July 26, 2021
Summary
Pediatric head and neck lymphoma, often presenting as tonsil asymmetry, requires careful diagnosis. Early detection of Burkitt
Area of Science:
- Pediatric Oncology
- Head and Neck Surgery
- Hematology
Background:
- Lymphoma is the most frequent childhood cancer affecting the head and neck.
- Clinical signs of palatine tonsil lymphoma include asymmetry, mucosal changes, and cervical lymphadenopathy.
- Unilateral tonsillar hypertrophy necessitates differentiation from infectious, chronic, or benign conditions.
Observation:
- A 14-year-old female presented with unilateral tonsillar enlargement and odynophagia.
- Symptoms persisted despite 21 days of antibiotic therapy.
- This clinical presentation led to the diagnosis of Burkitt's lymphoma.
Findings:
- The patient was diagnosed with Burkitt's lymphoma.
- Complete remission was achieved one year post-diagnosis.
Implications:
- This case highlights the importance of considering lymphoma in pediatric unilateral tonsillar hypertrophy.
- Prompt diagnosis and treatment are crucial for favorable outcomes in pediatric lymphoma.
- Further research into early diagnostic markers for pediatric head and neck lymphoma is warranted.
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