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Updated: Oct 26, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
Audiologic Characteristics of Hearing and Tinnitus in Occupational Noise-Induced Hearing Loss
Hee Jin Kang1, Zhe Jin2, Tong In Oh3
1Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Background:
To analyze the characteristics of patients with noise-induced hearing loss (NIHL) by comparing audiologic test findings between groups with and without tinnitus.
Methods:
This study involved patients with noise-induced hearing loss (NIHL) who presented to the otolaryngology clinic between January 2016 and April 2019. Tests including 3 pure-tone audiometry (PTA) tests at intervals greater than 1 week, and auditory brainstem response (ABR) were evaluated and patients were screened for tinnitus. The tinnitus patients had otoacoustic emission. Comparison was done between the tinnitus group and the group without tinnitus.
Results:
Of the 730 subjects with NIHL, 389 had tinnitus. PTA showed significantly higher thresholds at 2 kHz to 8 kHz in the tinnitus group. Although ABR tests tended to show more prolonged I, III, and V latency in the tinnitus group, the differences were not statistically significant. Distortion product otoacoustic emissions (DPOAE) showed more abnormalities at 3 kHz, and 4 kHz than at 1 kHz and 2 kHz. Transient otoacoustic emission (TEOAE) showed abnormal findings in both ears.
Conclusion:
In NIHL, hearing loss was more severe in patients with, than without tinnitus. DPOAE showed more abnormalities at 3 kHz, 4 kHz, and 6 kHz than at 1 kHz and 2 kHz, and TEOAE was abnormal at all frequencies.
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