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Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
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Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children
Dithi Banerjee1,2, Anjana Sasidharan1, Ayah Abdulhamid1
1Department of Pathology and Laboratory Medicine, Children's Mercy, Kansas City, Missouri, USA.
Journal of the Pediatric Infectious Diseases Society
|July 26, 2021
Abstract:
Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.

