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Chronic intracardiac thrombus, a long-term complication of COVID-19: Case reports

Umit Arslan1, Ferhat Borulu1, İbrahim Sarac2

  • 1Department of Cardiovascular Surgery, Ataturk University, Erzurum, Turkey.

Journal of Cardiac Surgery
|July 26, 2021
PubMed

Insights

Coronavirus disease 2019 (COVID-19) can cause long-term heart issues, including dangerous intracardiac thrombus, even after recovery. This study highlights two cases of chronic intracardiac thrombus in patients post-COVID-19 recovery.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathophysiology

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with significant inflammation and thrombogenic effects.
  • These effects can persist post-recovery, leading to serious cardiovascular complications.
  • Intracardiac thrombus formation is a critical, life-threatening complication that can result in sudden cardiac death.

Observation:

  • This study presents two cases of patients who had recovered from COVID-19.
  • Both patients presented with the development of chronic intracardiac thrombus.
  • The thrombus was identified after the acute phase of COVID-19 infection had resolved.

Findings:

  • The findings indicate a potential link between prior COVID-19 infection and the subsequent development of chronic intracardiac thrombus.
  • These cases underscore the prolonged cardiovascular risks associated with COVID-19.
  • The pathophysiology may involve persistent inflammatory and pro-thrombotic states induced by the virus.

Implications:

  • These observations suggest the need for vigilant cardiovascular monitoring in patients following COVID-19 recovery.
  • Early detection and management of intracardiac thrombus are crucial to prevent adverse outcomes such as sudden death.
  • Further research is warranted to elucidate the mechanisms linking COVID-19 to intracardiac thrombus and to establish optimal long-term management strategies.

Keywords:
COVID-19 infectionintracardiac thrombusopen-heart surgery

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