Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA as a Genetic Template02:05

DNA as a Genetic Template

24.2K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
24.2K
The DNA Helix01:16

The DNA Helix

150.1K
Overview
150.1K
The DNA Helix01:07

The DNA Helix

27.4K
Deoxyribonucleic acid, or DNA, is the genetic material responsible for passing traits from generation to generation in all organisms and most viruses. DNA is composed of two strands of nucleotides that wind around each other to form a spring-like structure called a double helix. However, the double helix is not perfectly symmetrical. Instead, there are regularly occurring grooves in the structure. The major groove occurs where the sugar-phosphate backbones are relatively far apart. This space...
27.4K
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

23.5K
Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
23.5K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

15.6K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
15.6K
DNA Packaging00:58

DNA Packaging

108.6K
Overview
108.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of Defect Geometry in Localized Emission from Monolayer Tungsten Dichalcogenides.

ACS nano·2026
Same author

Nonadiabatic Dynamics of Photoinduced Hydrogen Dissociation on Plasmonic Au Nanoparticles: How Hot Carrier Excitation Leads to Bond Breaking.

ACS nano·2026
Same author

Infrared Spectroelectrochemical Insights into Rhenium-Based Supramolecular Assemblies for Electron Storage and Transfer.

Inorganic chemistry·2026
Same author

Metal-Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids.

Angewandte Chemie (International ed. in English)·2026
Same author

Correction to "DNA-Mediated Cellular Delivery of Functional Enzymes".

Journal of the American Chemical Society·2026
Same author

High-χ Block Copolymer Nanoreactors for the Confined Synthesis of Size-Controlled Nanoclusters.

ACS nano·2026

Related Experiment Video

Updated: Oct 26, 2025

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.9K

Low-Density 2D Superlattices Assembled via Directional DNA Bonding.

Ziyi Miao1,2, Cindy Y Zheng3,2, George C Schatz3,2

  • 1Department of Materials Science and Engineering, Northwestern University, 2220 Campus Drive, Evanston, IL, 60208, USA.

Angewandte Chemie (International Ed. in English)
|July 26, 2021
PubMed
Summary

DNA nanotechnology enables precise nanoparticle assembly into novel 2D superlattices. Researchers discovered new low-density crystalline structures with potential for advanced metamaterials.

Keywords:
DNAcolloidal crystalsnanoparticle superlatticenanoparticlessmall-angle X-ray scattering

More Related Videos

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.7K
Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.2K

Related Experiment Videos

Last Updated: Oct 26, 2025

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

Published on: May 8, 2015

11.9K
Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
09:32

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules

Published on: April 12, 2019

6.7K
Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.2K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Supramolecular Chemistry

Background:

  • Precise assembly of nanoparticles (NPs) into superlattices is crucial for metamaterials.
  • Controlled symmetries and spacings on substrates dictate NP superlattice properties.
  • Bottom-up assembly techniques often yield high-density structures.

Purpose of the Study:

  • To utilize DNA for assembling anisotropic NPs into ordered 2D crystalline films on substrates.
  • To investigate the thermally induced reorganization of these NP assemblies.
  • To discover new low-density 2D superlattice structures.

Main Methods:

  • DNA-directed self-assembly of three anisotropic NP shapes: cubes, octahedra, and rhombic dodecahedra.
  • Assembly performed on substrates.
  • Analysis of thermally induced reorganization into 2D crystalline films.

Main Results:

  • Discovery of two novel low-density 2D nanoparticle superlattice structures.
  • Observation of a unique honeycomb lattice formed by octahedral NPs.
  • Demonstration that directional, face-to-face DNA bonds drive NP crystallization, consistent with the complementary contact model.

Conclusions:

  • DNA-directed assembly offers a route to novel low-density nanoparticle superlattices.
  • The findings provide insights into the driving forces of NP crystallization via DNA bonds.
  • This work enables the deliberate preparation of crystalline NP films with unique morphologies for metamaterials.