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![Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60445.jpg&w=3840&q=50)
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA
Published on: December 19, 2019
Case 296
Chen-Yen Lu1, Po-Chun Tseng1, Kuan-Chih Chen1
1From the Division of Gastroenterology and Hepatology, Department of Internal Medicine (C.Y.L., P.C.T., K.C.C., T.H.L., C.K.L., C.S.C.) and Department of Radiology (C.C.H., Y.M.T.), Far Eastern Memorial Hospital, 21 Nan-Ya South Rd, Section 2, Banciao District, New Taipei City, Taiwan 22060; and College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan (C.S.C.).
Abstract:
History A 55-year-old woman without systemic underlying disease, such as diabetes mellitus, inflammatory bowel disease, autoimmune disease, or chronic kidney disease, presented with generalized dull abdominal pain of 1-week duration. She had ingested herbal medicine for physical conditioning for several years. Laboratory findings, including biochemistry, electrolyte levels, and complete blood count, were all within normal limits, except for elevated serum C-reactive protein level (7.719 mg/dL; normal range,<1 mg/dL). The patient underwent initial evaluation with conventional abdominal radiography (Fig 1). She underwent subsequent evaluation with noncontrast CT of the abdomen (Figs 2, 3) and colonoscopy (Fig 4).
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