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Updated: Oct 26, 2025

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Aggravation of Reflux Finding Score (RFS) after thyroidectomy
Hyung-Joon Yoon1, Hee Ryung Kim1, Chang Myeon Song1
1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Thyroidectomy may worsen laryngopharyngeal reflux (LPR) symptoms and findings, with scores peaking post-surgery. Proton pump inhibitors can help manage these LPR changes after thyroid surgery.
Area of Science:
- Otolaryngology
- Gastroenterology
- Endocrinology
Background:
- Laryngopharyngeal reflux (LPR) is a suspected cause of post-thyroidectomy syndrome.
- The relationship between thyroidectomy and LPR requires further investigation.
Purpose of the Study:
- To evaluate the correlation between thyroidectomy and LPR.
- To assess changes in LPR symptoms and laryngoscopic findings pre- and post-thyroidectomy.
Main Methods:
- Ninety-five patients undergoing thyroidectomy were assessed.
- Reflux Finding Score (RFS) and Reflux Symptom Index (RSI) were measured pre-surgery and at 2, 4, 6, and 12 months post-surgery.
- Effect of proton pump inhibitors on RFS and RSI was evaluated.
Main Results:
- RFS scores significantly increased post-thyroidectomy, returning to baseline by 12 months.
- RSI scores showed a non-significant increase post-surgery, gradually decreasing over 12 months.
- Proton pump inhibitor administration improved both RSI and RFS scores.
Conclusions:
- Uncomplicated thyroidectomy can exacerbate LPR-related laryngoscopic findings.
- Further research with pH-monitoring and manometry is needed to understand LPR deterioration and upper esophageal sphincter pressure changes post-thyroidectomy.
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