Hypostability in the default mode network and hyperstability in the frontoparietal control network of dynamic
Xiao Chen 陈骁1, Chao-Gan Yan 严超赣1
1CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; International Big-Data Center for Depression Research, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing 100049, China.
Rumination involves altered brain stability, with decreased stability in the default mode network (DMN) and increased stability in the frontoparietal control network (FPCN). These brain stability changes relate to individual rumination tendencies.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
- Psychiatry
Background:
- Rumination, a repetitive thought process, has distinct neural dynamics.
- Temporal stability, representing consistent neural activity patterns, is crucial for brain function but its role in rumination is unclear.
Purpose of the Study:
- To investigate the temporal stability of whole-brain functional architecture during induced rumination.
- To compare rumination-induced stability with a distraction state and resting state.
- To explore the relationship between neural stability, rumination traits, and functional connectivity (FC).
Main Methods:
- Functional connectivity (FC) analysis was used in 40 healthy participants.
- Participants underwent induced rumination and distraction states.
- Whole-brain functional architecture stability was assessed and correlated with rumination traits.
Main Results:
- Rumination exhibited an altered stability profile compared to distraction and resting states.
- Default mode network (DMN) regions (medial prefrontal cortex, parahippocampal gyrus) showed decreased stability.
- Frontoparietal control network (FPCN) regions (inferior parietal lobule, dorsal lateral prefrontal cortex) showed increased stability.
- Stability in the medial prefrontal cortex and inferior parietal lobule correlated with individual rumination traits.
Conclusions:
- Rumination is characterized by dissociated neural stability: hypostability in the DMN and hyperstability in the FPCN.
- These stability patterns may reflect the underlying neural mechanisms of rumination.
- Individual differences in rumination are associated with specific regional stability variations.
More Related Videos
08:42Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
Published on: May 19, 2015
09:14Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Related Concept Videos
Functional Brain Systems: Reticular Formation
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
High-Level and Low-Level Awareness
Role of Cerebellum and Prefrontal Cortex in Memory
