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A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
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In vitro anti-Leishmania activity and molecular docking of spiro-acridine compounds as potential multitarget agents

Fernanda S Almeida1, Gleyton L S Sousa2, Juliana C Rocha3

  • 1Programa de Doutorado em Biotecnologia, Rede Nordeste de Biotecnologia, Universidade Federal da Paraíba, João Pessoa, PB 58051-900, Brazil; Laboratório de Imunologia das Doenças Infeciosas, Universidade Federal da Paraíba, João Pessoa, PB 58051-900, Brazil.

Bioorganic & Medicinal Chemistry Letters
|July 26, 2021
PubMed

Keywords:
Acridine compoundsAntileishmanial activityLeishmaniasisMultitarget agentStructure-activity relationship

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