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Updated: Oct 26, 2025

Fluorescence detection methods for microfluidic droplet platforms
Published on: December 10, 2011
Determination of dynamic interactions of droplets in continuous fluids using droplet probe
Wenjie Lan1, Dizong Cai1, Xiaojie Hu1
1State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Beijing 102249, China.
Hypothesis:
Interactions between droplets are of fundamental importance for understanding phenomena involving droplet collision and coalescence that determine multiphase flow behavior. The quantitative understanding of these interactions is essential for the manipulation and control of emulsions or complex fluids. The existing methods for interaction force determination are typically based on expensive mechanical probes and fine distance control. Therefore, further development of new techniques for interaction force determination is expected to be beneficial for research on surface force.
Experiments:
In this study, droplet deformation during the interaction between two droplets was captured and analyzed to determine the interaction force. The approach speed of the two droplets was controlled by the injection rate of the fluid. The dynamic interaction force between two tetradecane droplets in various aqueous solutions was determined using the newly developed method, and the effects of two-phase physical properties and operating conditions on the measurement errors were investigated.
Findings:
The droplet profile deformation was first applied as a probe to detect the interaction force. The measurement results were in good agreement with those obtained using the precise weighing sensor of a commercial interfacial tensiometer (K100, Kruss, Germany). The newly developed method was reliable, simple, and did not require the use of expensive devices. Furthermore, droplet deformability was found to be the key parameter in determining the total interaction force between the droplets.

