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Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
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Updated: Oct 26, 2025

User-friendly, High-throughput, and Fully Automated Data Acquisition Software for Single-particle Cryo-electron Microscopy
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Community-Driven Methods for Open and Reproducible Software Tools for Analyzing Datasets from Atom Probe Microscopy.

Markus Kühbach1, Andrew J London2, Jing Wang3

  • 1Max-Planck-Institut für Eisenforschung GmbH, Max-Planck-Straße 1, D-40237Düsseldorf, Germany.

Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
|July 27, 2021
PubMed
Summary
This summary is machine-generated.

Developing standardized software workflows for atom probe microscopy is crucial. Sharing these open-source tools and data improves material characterization accuracy, efficiency, and user training.

Keywords:
Atom probe microscopyFAIRresearch data managementsoftware developmentuncertainty quantification

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Area of Science:

  • Materials Science
  • Computational Science

Background:

  • Atom probe tomography (APT) and related methods are vital for characterizing material composition and 3D architecture.
  • The accuracy and precision of APT experiments heavily rely on software tools and their integration into workflows.
  • Current practices often involve adapting methods from diverse fields like data science and artificial intelligence.

Purpose of the Study:

  • To address challenges in research data management and align with FAIR data stewardship principles in atom probe microscopy.
  • To foster collaboration and develop standardized test cases for atom probe microscopy software tools across different laboratories.

Main Methods:

  • An inter-laboratory call was initiated to develop test cases for various atom probe microscopy software tools.
  • Focus on defining and sharing detailed software workflow recipes.

Main Results:

  • The initiative highlighted the necessity and benefits of defining and sharing detailed software workflow recipes.
  • Open-source tools and standardized (meta)data exchange were identified as key facilitators.

Conclusions:

  • Sharing software workflows enhances the efficiency of data processing in atom probe microscopy.
  • Standardization aids in user training, knowledge transfer, and automated uncertainty quantification for reliable results.