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Related Concept Videos

Steady State Concentration01:05

Steady State Concentration

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A steady state refers to the level of a drug in the body once it has reached an equilibrium between administration and elimination. It represents the point at which the drug administration rate equals the drug elimination rate, resulting in a relatively constant concentration in the body over time. The dynamic equilibrium is crucial to ensure the drug's effectiveness with minimal risk of toxicity.
Most drugs are administered in repeated doses at fixed intervals or through continuous...
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Smooth Muscle Contraction01:25

Smooth Muscle Contraction

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Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
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Time Course of Drug Effect01:14

Time Course of Drug Effect

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The progression of a drug's impact can be analyzed by examining both the concentration-time course and the effect-time course. The concentration-time course is determined by the drug's half-life and is influenced by factors such as its pharmacokinetics, including absorption, distribution, metabolism, and elimination. The effect of the drug is often related to its concentration in the plasma and is calculated using the maximum drug effect and the plasma concentration that generates 50...
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Decreased pulse rate01:14

Decreased pulse rate

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Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
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Dosage Regimen: Multiple Oral Dosage01:25

Dosage Regimen: Multiple Oral Dosage

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Understanding how a drug's concentration fluctuates within the body over time is crucial in pharmacokinetics, particularly with multiple oral doses. A graphical representation of multiple oral dosages provides insight into these dynamics. Typical accumulation curves of a drug's concentration in the body reveal a sawtooth pattern, indicating periodic peaks and troughs correlating with each dose administration and the drug's subsequent elimination.The plasma concentration at any time during an...
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Compartment Models: Two-Compartment Model01:20

Compartment Models: Two-Compartment Model

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The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
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Measurement of Smooth Muscle Function in the Isolated Tissue Bath-applications to Pharmacology Research
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Measurement of Smooth Muscle Function in the Isolated Tissue Bath-applications to Pharmacology Research

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Slow Medicine.

Elena Hill1

  • 1From the Family Medicine Attending Physician, Bronxcare Health Systems, Bronx, NY (EH). ehill3047@gmail.com.

Journal of the American Board of Family Medicine : JABFM
|July 27, 2021
PubMed
Summary
This summary is machine-generated.

Fast medicine, characterized by high medical use and spending, is contrasted with "slow medicine," emphasizing primary care. The piece argues for the superior health outcomes and value derived from slow medicine, advocating for increased primary care resources.

Keywords:
Delivery of Health CareEthicsHealth ResourcesPrimary Health Care

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Area of Science:

  • Medical Ethics
  • Health Services Research
  • Primary Care Medicine

Background:

  • The current healthcare system often prioritizes high-cost interventions over preventative care.
  • A dichotomy exists between

Purpose of the Study:

  • To examine the ethical considerations of

Main Methods:

  • This is an opinion piece, drawing on a personal patient case study.
  • Ethical analysis of medical decision-making.

Main Results:

  • The case study highlights the risks associated with aggressive interventions.
  • Primary care, or "slow medicine," is presented as a more effective framework for conferring patient health.

Conclusions:

  • Advocacy for increased investment in primary care resources is crucial.
  • Slow medicine offers a more sustainable and effective model for improving overall patient health outcomes.