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[Chronic pancreatitis. Surgical therapy by resection procedures]
1Chirurgische Klinik mit Poliklinik, Universität Erlangen-Nürnberg.
Langenbecks Archiv Fur Chirurgie
|January 1, 1987
Summary
Surgical outcomes for pancreatic cancer improved significantly with advancements in resection techniques. Partial duodeno-pancreatectomy with duct occlusion demonstrated a low operative mortality and excellent long-term pain relief.
Area of Science:
- Gastroenterology and Surgical Oncology
- Pancreatic Surgery Outcomes
Context:
- Evaluation of surgical techniques for pancreatic cancer treatment.
- Historical comparison of operative mortality rates.
Purpose:
- To assess the efficacy and safety of different pancreatic resection methods.
- To analyze long-term outcomes including mortality, pain, and recurrence.
Summary:
- Operative mortality decreased from 10% to 1.2% across 606 resections.
- Distal resections yielded good results in 66% of cases with 11% late mortality.
- Partial duodeno-pancreatectomy with Ethibloc duct occlusion showed 1% operative mortality, 88% pain-free survival, and 2.1% recurrence.
Impact:
- Total pancreatectomy was discontinued due to 40% mortality.
- Demonstrated successful preservation of endocrine function.
- Established partial duodeno-pancreatectomy as a safer, effective alternative.