Related Experiment Video

Updated: Oct 26, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.4K

Physical functioning in patients with chronic kidney disease stage G3b-5 in Japan: The reach-J CKD cohort study

Reiko Okubo1,2, Masahide Kondo1, Ryoya Tsunoda2

  • 1Department of Health Care Policy and Health Economics, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Nephrology (Carlton, Vic.)
|July 27, 2021
PubMed

Insights

A significant number of patients with advanced chronic kidney disease (CKD) experience poor physical functioning and inactivity. Nephrologists should assess physical activity and function in CKD patients for better daily life support.

Area of Science:

  • Nephrology
  • Geriatrics
  • Public Health

Background:

  • Chronic kidney disease (CKD) is a growing public health concern.
  • Previous studies link CKD to diminished physical functioning in community-dwelling elderly.
  • The physical functioning of non-dialysis (ND) patients with advanced CKD is not well understood.

Purpose of the Study:

  • To investigate the physical functioning and physical activity levels of non-dialysis (ND) patients with advanced CKD (stages G3b-5).
  • To identify factors associated with poor physical functioning and physical inactivity in this patient group.

Main Methods:

  • Analysis of data from 1628 patients in the nationwide Reach-J CKD cohort study.
  • Assessment of physical functioning using Katz Index and Lawton-Body instrumental activities of daily living (IADL) scale.
  • Evaluation of physical activity using the Rapid Assessment of Physical Activity questionnaire.

Main Results:

  • 84.3% of patients exhibited good physical functioning.
  • Poor physical functioning was associated with older age, higher CKD stage, and comorbidities like diabetes, cardiovascular disease, cerebrovascular disease, and cancer.
  • 40% of patients were physically inactive, with inactivity more prevalent in older patients and those with higher CKD stages.

Conclusions:

  • A notable proportion of advanced CKD patients receiving nephrologist care experience limitations in activities of daily living (ADLs) and instrumental ADLs (IADLs).
  • Routine assessment of physical functioning and activity by nephrologists is crucial for providing tailored guidance and support.
  • This proactive approach can enhance the daily lives of patients with advanced CKD.
Abstract

Keywords:
chronic kidney diseasedisabilityphysical activityphysical functioningreach-J study

More Related Videos

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.0K
A Murine Model of Hemodialysis Access-Related Hand Dysfunction08:39

A Murine Model of Hemodialysis Access-Related Hand Dysfunction

Published on: May 31, 2022

1.8K

Related Concept Videos

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
193
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
154
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
284
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
99
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
37
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
337