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Tracking Pandemic Severity Using Data on the Age Structure of Mortality: Lessons From the 1918 Influenza Pandemic in
Siddharth Chandra1, Julia Christensen1
1Siddharth Chandra is with the Asian Studies Center and James Madison College at Michigan State University, East Lansing, with a courtesy appointment in the Department of Epidemiology and Biostatistics. Julia Christensen is with James Madison College at Michigan State University, East Lansing.
Abstract:
Objectives. To test whether distortions in the age structure of mortality during the 1918 influenza pandemic in Michigan tracked the severity of the pandemic. Methods. We calculated monthly excess deaths during the period of 1918 to 1920 by using monthly data on all-cause deaths for the period of 1912 to 1920 in Michigan. Next, we measured distortions in the age distribution of deaths by using the Kuiper goodness-of-fit test statistic comparing the monthly distribution of deaths by age in 1918 to 1920 with the baseline distribution for the corresponding month for 1912 to 1917. Results. Monthly distortions in the age distribution of deaths were correlated with excess deaths for the period of 1918 to 1920 in Michigan (r = 0.83; P < .001). Conclusions. Distortions in the age distribution of deaths tracked variations in the severity of the 1918 influenza pandemic. Public Health Implications. It may be possible to track the severity of pandemic activity with age-at-death data by identifying distortions in the age distribution of deaths. Public health authorities should explore the application of this approach to tracking the COVID-19 pandemic in the absence of complete data coverage or accurate cause-of-death data.
Insights
Distortions in death age distribution during the 1918 influenza pandemic correlated with pandemic severity. This method may help track future pandemics like COVID-19 using age-at-death data.
Area of Science:
- Epidemiology
- Demography
Background:
- The 1918 influenza pandemic caused significant mortality, with notable age distribution shifts.
- Understanding pandemic severity tracking is crucial for public health preparedness.
Observation:
- Excess deaths in Michigan from 1918-1920 were calculated using all-cause mortality data.
- The Kuiper goodness-of-fit test measured deviations in monthly age-at-death distributions compared to a 1912-1917 baseline.
Findings:
- A strong positive correlation (r=0.83, P<.001) was found between monthly age distribution distortions and excess deaths.
- These findings indicate that changes in the age structure of mortality mirrored pandemic intensity.
Implications:
- Age distribution of deaths can serve as a proxy for tracking pandemic severity.
- This approach offers a potential method for monitoring pandemics, including COVID-19, especially when complete data is lacking.
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