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Updated: Oct 26, 2025

04:41
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
Published on: March 10, 2023
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Unexpected diagnosis for nodular hepatic lesions
Isabel Garrido1, Rosa Coelho2, Joanne Lopes3
1Gastrenterology and Hepatology, Centro Hospitalar Universitário de São João, Portugal.
Revista Espanola De Enfermedades Digestivas
|July 28, 2021
Summary
Late recurrence of uveal melanoma, a common eye cancer that often spreads to the liver, is extremely rare. Most metastases appear within the first few years post-treatment.
Area of Science:
- Ophthalmology
- Oncology
- Medical Research
Background:
- Uveal melanoma is the most frequent primary tumor affecting the eye.
- Liver metastasis is the predominant pattern of spread for uveal melanoma.
- Current understanding suggests metastases typically manifest early after primary treatment.
Discussion:
- This study addresses the rarity of late recurrence in uveal melanoma.
- It highlights the typical timeframe for metastatic presentation.
- The findings emphasize the importance of long-term surveillance, albeit with a low expectation for late events.
Key Insights:
- Late recurrence of uveal melanoma is exceptionally uncommon.
- The vast majority of metastatic uveal melanoma cases present within the initial years post-treatment.
- This observation refines prognostic expectations for patients.
Outlook:
- Further research could explore potential biological mechanisms underlying the rarity of late metastasis.
- Long-term follow-up protocols may be informed by this understanding.
- This knowledge aids in patient counseling regarding prognosis and surveillance.

