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Frequency and Causes of Delirium in Pediatric Intensive Care Unit: A Prospective Observational Study
Ahmet Yontem1, Dincer Yildizdas1, Ozden O Horoz1
1Department of Pediatric Intensive Care, Cukurova University Medicine Faculty, Adana, Turkey.
Insights
Pediatric delirium occurred in 9.9% of critically ill children. Psychosocial interventions significantly reduced delirium risk, highlighting their importance in pediatric intensive care units.
Area of Science:
- Pediatric critical care medicine
- Neuroscience
- Psychiatry
Background:
- Pediatric delirium is increasingly studied in critically ill children.
- This study aimed to determine the frequency and risk factors of pediatric delirium in a pediatric intensive care unit (PICU).
Observation:
- The study evaluated patients hospitalized in the PICU between November 1, 2018, and August 31, 2019, for over 48 hours.
- Delirium was detected in 9.9% of patients.
- Higher PIM2 scores and longer PICU stays were associated with delirium.
Findings:
- Patients with delirium had increased use of respiratory support, sedation-analgesia, vasoactive drugs, corticosteroids, and physical restraints.
- Psychosocial interventions were associated with a significantly lower likelihood of developing delirium (OR, 0.237; p = 0.044).
- Each additional day in the PICU independently increased the odds of delirium (OR, 1.095; p = 0.037).
Implications:
- Risk factors for pediatric delirium align with previous research.
- Early psychosocial intervention may be a protective strategy against delirium in critically ill children.
- Multicenter randomized controlled trials are recommended to validate these findings.
Background:
The number of studies evaluating delirium and its frequency in critically ill infants, children, and adolescents is increasing day by day. The primary objective of this study was to evaluate all patients hospitalized in our pediatric intensive care unit (PICU) in terms of pediatric delirium, to determine the frequency and risk factors of pediatric delirium.
Patients And Methods:
The patients included in this study had been hospitalized in the PICU between November 1, 2018, and August 31, 2019, and were followed up for more than 48 hours.
Results:
Delirium was detected in 14 patients (9.9%) through regular evaluations. The Pediatric Index of Mortality 2 (PIM2) scores and the length of stay in the PICU were higher in patients with delirium (p = 0.03 and p = 0.01, respectively). The use of respiratory support, sedation-analgesia, vasoactive and corticosteroid treatments, and physical restraints were higher in patients with delirium and were statistically significant (p <0.05). Following admission to the PICU, psychosocial interventions were implemented for 76.1% of the whole cohort. Delirium developed in only five (4.5%) of the 108 patients who underwent psychosocial interventions, while it was detected in nine (26.5%) of the 34 patients who did not receive psychosocial interventions (p = 0.001). The psychosocial intervention was associated with a lower likelihood of delirium (odds ratio [OR], 0.237; p = 0.044). An increasing number of days in the PICU was independently associated with increasing odds of delirium (OR, 1.095; p = 0.037 for each day).
Conclusions:
We observed that the risk factors associated with delirium were similar to previous studies. Additionally, psychosocial intervention before delirium symptoms developed was associated with a lower risk of developing delirium. However, multicenter randomized controlled trials are needed on this subject.
How To Cite This Article:
Yontem A, Yildizdas D, Horoz OO, et al. Frequency and Causes of Delirium in Pediatric Intensive Care Unit: A Prospective Observational Study. Indian J Crit Care Med 2021;25(6):715-719.
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