Frequency and Causes of Delirium in Pediatric Intensive Care Unit: A Prospective Observational Study

Ahmet Yontem1, Dincer Yildizdas1, Ozden O Horoz1

  • 1Department of Pediatric Intensive Care, Cukurova University Medicine Faculty, Adana, Turkey.

Insights

Pediatric delirium occurred in 9.9% of critically ill children. Psychosocial interventions significantly reduced delirium risk, highlighting their importance in pediatric intensive care units.

Area of Science:

  • Pediatric critical care medicine
  • Neuroscience
  • Psychiatry

Background:

  • Pediatric delirium is increasingly studied in critically ill children.
  • This study aimed to determine the frequency and risk factors of pediatric delirium in a pediatric intensive care unit (PICU).

Observation:

  • The study evaluated patients hospitalized in the PICU between November 1, 2018, and August 31, 2019, for over 48 hours.
  • Delirium was detected in 9.9% of patients.
  • Higher PIM2 scores and longer PICU stays were associated with delirium.

Findings:

  • Patients with delirium had increased use of respiratory support, sedation-analgesia, vasoactive drugs, corticosteroids, and physical restraints.
  • Psychosocial interventions were associated with a significantly lower likelihood of developing delirium (OR, 0.237; p = 0.044).
  • Each additional day in the PICU independently increased the odds of delirium (OR, 1.095; p = 0.037).

Implications:

  • Risk factors for pediatric delirium align with previous research.
  • Early psychosocial intervention may be a protective strategy against delirium in critically ill children.
  • Multicenter randomized controlled trials are recommended to validate these findings.
Abstract

Related Concept Videos

Assessment of Ventilation I: Respiratory Rate01:20

Assessment of Ventilation I: Respiratory Rate

Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
1.5K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
57
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
47
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
57
Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.0K
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
202