Fundus Examination to Guide Anticoagulation Therapy in Suspected COVID-19 in a Critical Care Unit

Rini Saha1, Subodh K Singh1, Sukhen Samanta2

  • 1Department of Ophthalmology, IRIS Super Speciality Eye Hospital, Ranchi, Jharkhand, India.

Insights

Ophthalmological fundus examination can reveal critical information about COVID-19 patients. This non-invasive technique may help guide anticoagulation therapy decisions in intensive care settings.

Area of Science:

  • Ophthalmology
  • Critical Care Medicine
  • Infectious Diseases

Background:

  • COVID-19 is associated with a hypercoagulable state and increased risk of thrombotic events.
  • Anticoagulation therapy is crucial for managing critically ill COVID-19 patients.
  • Ocular manifestations of COVID-19, including retinal changes, have been reported.

Purpose of the Study:

  • To explore the utility of fundus examination in assessing COVID-19-related coagulopathy.
  • To determine if fundus findings can inform anticoagulation therapy in critical care.

Main Methods:

  • A critical care unit setting was used for the study.
  • Fundus examinations were performed on patients with suspected COVID-19.
  • Clinical data, including anticoagulation status, were correlated with fundus findings.

Main Results:

  • Specific retinal vascular changes were observed in patients with COVID-19.
  • These fundus findings may indicate underlying thrombotic activity.
  • The study suggests a potential link between fundus appearance and the need for anticoagulation.

Conclusions:

  • Fundus examination offers a valuable, non-invasive method to assess systemic vascular status in COVID-19.
  • Ophthalmological findings can potentially guide the intensity and duration of anticoagulation therapy.
  • Integrating fundus examination into critical care protocols may improve patient management.

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