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Updated: Oct 26, 2025

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On the impact of batch effect correction in TCGA isomiR expression data

Susanne Ibing1, Birgitta E Michels2, Moritz Mosdzien2

  • 1Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Berliner Straße 41, 69120 Heidelberg, Germany.

NAR Cancer
|July 28, 2021
PubMed
Summary

Batch effects in The Cancer Genome Atlas (TCGA) data can obscure important findings. This study corrected isomiR expression data, revealing crucial tumor-suppressive microRNA (miRNA) roles in lung cancer.

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