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Updated: Oct 26, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Timely Management of Obstructive Prosthetic Valve Thrombosis
Elona Rrapo Kaso1, Steve A Noutong1, LeAnn N Denlinger1
1Division of Cardiovascular Medicine, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Abstract:
Obstructive bioprosthetic valve thrombosis is associated with hemodynamic compromise, and evidence on management with fibrinolysis is limited. Echocardiography is required to assess thrombus size and its effects on valve gradients, area, and leaflet motion. This case demonstrates use of echocardiography guided slow-infusion low-dose fibrinolytic therapy in a patient with obstructive bioprosthetic valve thrombosis. (Level of Difficulty: Intermediate.).
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