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Updated: Oct 26, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
A Challenging and Unexpected Case of MINOCA Using Multimodality Imaging
Matthew G L Williams1,2, Charlotte Thompson1,2, Thomas W Johnson1
1Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.
Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) can be challenging to diagnose. This case shows isolated right ventricular myocardial infarction with microvascular obstruction missed by standard assessments.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Diagnostic Medicine
Background:
- Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) presents diagnostic challenges.
- Standard diagnostic pathways may not always identify the underlying cause of MINOCA.
- Right ventricular myocardial infarction is a less common but significant presentation.
Observation:
- A case of MINOCA was investigated, presenting with isolated right ventricular myocardial infarction.
- Cardiac magnetic resonance imaging (CMR) was utilized for detailed cardiac assessment.
- The patient's initial comprehensive, guideline-based assessment did not reveal the specific pathology.
Findings:
- Cardiac MRI successfully identified microvascular obstruction as the cause of myocardial infarction.
- The findings indicate isolated right ventricular involvement.
- This highlights a specific scenario where standard assessments may be insufficient.
Implications:
- This case underscores the importance of advanced imaging like CMR in diagnosing MINOCA.
- It suggests that microvascular dysfunction should be considered even with initial negative findings.
- Further refinement of diagnostic strategies for MINOCA may be warranted.
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