Related Experiment Video
Updated: Oct 26, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Pressure-Volume Loop Analysis in Percutaneous Coronary Intervention-Induced Shock
Admir Dedic1, Marcelo B Bastos1, Nicolas M Van Mieghem1
1Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Insights
High-risk percutaneous coronary intervention can cause cardiogenic shock. This study analyzes hemodynamic changes during such events using pressure-volume loop analysis, offering insights into percutaneous coronary intervention-induced shock.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- High-risk percutaneous coronary intervention (PCI) is associated with serious complications.
- Cardiogenic shock is a critical adverse event that can occur post-PCI.
Purpose of the Study:
- To describe the hemodynamic alterations observed during percutaneous coronary intervention-induced shock.
- To utilize pressure-volume loop analysis for detailed hemodynamic assessment in this context.
Main Methods:
- The study involved patients undergoing high-risk PCI.
- Hemodynamic parameters were analyzed using pressure-volume loop measurements.
- The PULsecath mechanicaL Support Evaluation (PULSE) study (NCT03200990) provided the data.
Main Results:
- Detailed hemodynamic changes during PCI-induced shock were characterized.
- Pressure-volume loop analysis revealed specific patterns of cardiac dysfunction.
Conclusions:
- Pressure-volume loop analysis is a valuable tool for understanding hemodynamics in PCI-induced shock.
- Insights gained can inform management strategies for high-risk PCI patients.
Abstract:
High-risk percutaneous coronary intervention may lead to undesirable clinical scenarios such as cardiogenic shock. We describe the hemodynamic changes using pressure-volume loop analyses in percutaneous coronary intervention-induced shock. (PULsecath mechanicaL Support Evaluation [PULSE]; NCT03200990) (Level of Difficulty: Intermediate.).

