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Related Concept Videos

Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

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Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
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Updated: Oct 26, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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Pressure-Volume Loop Analysis in Percutaneous Coronary Intervention-Induced Shock.

Admir Dedic1, Marcelo B Bastos1, Nicolas M Van Mieghem1

  • 1Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands.

JACC. Case Reports
|July 28, 2021
PubMed
Summary

High-risk percutaneous coronary intervention can cause cardiogenic shock. This study analyzes hemodynamic changes during such events using pressure-volume loop analysis, offering insights into percutaneous coronary intervention-induced shock.

Keywords:
ICU, intensive care unitLAD, left anterior descending coronary arteryLV, left ventriclecardiac assist deviceshemodynamicspercutaneous coronary intervention

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • High-risk percutaneous coronary intervention (PCI) is associated with serious complications.
  • Cardiogenic shock is a critical adverse event that can occur post-PCI.

Purpose of the Study:

  • To describe the hemodynamic alterations observed during percutaneous coronary intervention-induced shock.
  • To utilize pressure-volume loop analysis for detailed hemodynamic assessment in this context.

Main Methods:

  • The study involved patients undergoing high-risk PCI.
  • Hemodynamic parameters were analyzed using pressure-volume loop measurements.
  • The PULsecath mechanicaL Support Evaluation (PULSE) study (NCT03200990) provided the data.

Main Results:

  • Detailed hemodynamic changes during PCI-induced shock were characterized.
  • Pressure-volume loop analysis revealed specific patterns of cardiac dysfunction.

Conclusions:

  • Pressure-volume loop analysis is a valuable tool for understanding hemodynamics in PCI-induced shock.
  • Insights gained can inform management strategies for high-risk PCI patients.