"Catch Me If You Can": Recurrent ST-Segment Elevation Myocardial Infarction Due to Aortic Thrombus
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Updated: Oct 26, 2025

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Xinzhe James Cai1, Thuan Ngee Tan1, Siang Chew Chai1
1Department of Cardiology, Changi General Hospital, Singapore.
Insights
A mobile aortic thrombus prolapsing into the right coronary ostium caused recurrent myocardial infarction in a patient with minimal coronary artery disease. This rare finding highlights the need for comprehensive cardiac imaging to identify unusual causes of heart attacks.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Interventional Cardiology
Background:
- Recurrent ST-segment elevation myocardial infarction (STEMI) necessitates thorough etiological investigation, especially in cases with minimal atherosclerotic burden.
- Aortic valve thrombus is an uncommon cause of coronary artery occlusion and myocardial infarction.
Observation:
- A 42-year-old male experienced recurrent inferior STEMI despite minimal coronary atherosclerosis identified on intracoronary imaging.
- Transesophageal echocardiogram and CT aortogram revealed a mobile thrombus originating from the right coronary cusp.
Findings:
- The aortic thrombus was observed to prolapse into and out of the right coronary ostium, intermittently obstructing coronary blood flow.
- This mechanical obstruction by the aortic thrombus was identified as the cause of the recurrent myocardial infarctions.
Implications:
- This case underscores the importance of considering non-atherosclerotic causes of myocardial infarction, particularly mobile aortic thrombi.
- Advanced cardiovascular imaging modalities are crucial for diagnosing rare cardiac pathologies causing ischemic events.
- Prompt identification and management of aortic thrombi are essential to prevent recurrent ischemic events and improve patient outcomes.
Abstract:
A 42-year-old male patient presented with recurrent inferior ST-segment elevation myocardial infarction with minimal atherosclerotic disease on intracoronary imaging. Transesophageal echocardiogram and computed tomography aortogram revealed the underlying cause to be a mobile aortic thrombus in the right coronary cusp, prolapsing into and out of the right coronary ostium. (Level of Difficulty: Beginner.).
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