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Updated: Oct 26, 2025

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Ventriculoseptal Rupture Caused by Takotsubo Syndrome
Michael E Sternberg1, Zachary M Gertz2, Mohammed A Quader3
1Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia.
Abstract:
Ventriculoseptal rupture (VSR) is a rare complication of takotsubo syndrome that often requires immediate treatment. Patients with VSR experience a range of outcomes and should be managed at centers with cardiac and surgical expertise. We present 2 cases of VSR complicating takotsubo syndrome that highlight potential outcomes. (Level of Difficulty: Intermediate.).
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