Atrial Thrombosis Caused by a Dislocated Left Atrial Appendage Closure Device After Mitral Valve Replacement

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Updated: Oct 26, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Moritz B Immohr1, Yukiharu Sugimura1, Artur Lichtenberg1

  • 1Department of Cardiac Surgery, Medical School, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

A left atrial appendage occlusion device dislocated after mitral valve replacement, causing thrombosis and myocardial infarction. Alternative appendage occlusion methods might prevent such serious postoperative complications.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Left atrial appendage occlusion (LAAAO) devices are used to prevent stroke in patients with atrial fibrillation.
  • Mitral valve replacement (MVR) is a common cardiac surgical procedure.

Observation:

  • A patient with an LAAAO device experienced dislocation of the device following MVR.
  • This dislocation led to the formation of left atrial thrombosis.

Findings:

  • The left atrial thrombosis, resulting from device dislocation, caused a thromboembolic myocardial infarction.
  • The patient suffered significant postoperative complications attributed to the dislodged LAAAO device.

Implications:

  • Device-based LAAAO may carry risks of dislocation and subsequent thromboembolic events, especially after concurrent cardiac procedures.
  • Non-device-based or alternative LAAAO strategies could potentially mitigate risks associated with device migration and associated complications.

Keywords:
AF, atrial fibrillationLA, left atriumLAA, left atrial appendageLAAO, left atrial appendage occlusionatrial fibrillationleft atrial appendagemitral valvethrombosisvalve replacement

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