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Late Atrial Thrombus Formation After Percutaneous Patent Foramen Ovale Closure

Manjari R Regmi1, Odalys Estefania Lara Garcia1, Priyanka Parajuli1

  • 1Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

Late thrombus formation is a rare complication after patent foramen ovale (PFO) closure. This case highlights the need for vigilance, as large atrial thrombi were discovered 9 months post-procedure, necessitating cardiac surgery.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Patent foramen ovale (PFO) is a common cardiac anomaly.
  • Percutaneous PFO closure is a standard treatment option.
  • Late complications after PFO closure are uncommon but can be serious.

Observation:

  • A case of incidental discovery of large thrombi in both atria is presented.
  • The thrombi were found 9 months after percutaneous PFO occlusion.
  • The patient required cardiac surgery for thrombi removal.

Findings:

  • Late thrombus formation is a rare but significant complication of PFO closure devices.
  • Atrial thrombi can develop months after successful PFO occlusion.
  • Surgical intervention may be necessary for managing large thrombi post-PFO closure.

Implications:

  • This case underscores the importance of considering rare complications after PFO closure.
  • Further research may be needed to understand the mechanisms and risk factors for late thrombus formation.
  • Clinicians should maintain a high index of suspicion for thromboembolic events in patients with PFO closure devices.

Keywords:
CT, computed tomographyPE, pulmonary embolismPFO, patent foramen ovaleTEE, transesophageal echocardiogramTTE, transthoracic echocardiogramoccluder devicepatent foramen ovaleperipheral vascular diseasestrokethrombus

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