Coronary Artery Occlusion Caused by Intramural Hematoma Due to In-Stent Dissection

Yasushi Ueki1, Lorenz Räber1, Raminta Kavaliauskaite1

  • 1Department of Cardiology, Bern University Hospital, Bern, Switzerland.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

In-stent dissection after percutaneous coronary intervention can lead to intramural hematoma and coronary artery occlusion. This case highlights a rare complication of a typically benign finding, emphasizing the need for careful monitoring.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Percutaneous coronary intervention (PCI) is a common procedure for coronary artery disease.
  • In-stent dissection is a frequent finding during PCI, often considered benign.
  • Complications from in-stent dissections can occur, though rarely.

Purpose of the Study:

  • To report a case of ST-segment elevation myocardial infarction (STEMI) secondary to in-stent dissection.
  • To illustrate the potential for in-stent dissection to cause intramural hematoma and coronary occlusion.
  • To emphasize the importance of advanced imaging in diagnosing PCI complications.

Main Methods:

  • A 54-year-old male patient presented with STEMI.
  • Emergent PCI was performed on the left anterior descending artery.
  • Optical coherence tomography (OCT) was utilized for in-situ imaging during PCI.

Main Results:

  • OCT revealed an intramural hematoma originating from an in-stent dissection.
  • The intramural hematoma extended and led to coronary artery occlusion.
  • The patient experienced STEMI one week post-PCI.

Conclusions:

  • In-stent dissection, while often benign, can progress to serious complications.
  • Intramural hematoma formation is a potential sequela of in-stent dissection.
  • OCT is crucial for identifying and characterizing such complications during PCI.

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
180
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
58
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
95
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
111