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Related Experiment Video

Updated: Oct 26, 2025

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

Tropical Endomyocardial Fibrosis.

Joanne S Sutter¹, Tisha M Suboc¹, Anupama K Rao¹

¹Department of Cardiology, Rush University Medical Center, Chicago, Illinois.

JACC. Case Reports

|July 28, 2021

Summary

Tropical endomyocardial fibrosis, a cause of restrictive cardiomyopathy, can affect the right ventricle. This case highlights the importance of accurate diagnosis to avoid confusion with similar conditions like Ebstein

Keywords:

CMR, cardiac magnetic resonance EMF, endomyocardial fibrosis LGE, late gadolinium enhancement RV, right ventricular TTE, transthoracic echocardiogram cardiac magnetic resonance cardiomyopathy fibrosis restrictive right ventricle

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Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

Published on: February 28, 2018

Area of Science:

Cardiology
Tropical Medicine
Pathology

Background:

Endomyocardial fibrosis (EMF) is a primary cause of restrictive cardiomyopathy globally.
While prevalent in tropical regions, EMF is uncommon in developed nations.
Restrictive cardiomyopathy presents diagnostic challenges, particularly in differentiating from other cardiac anomalies.

Observation:

A case of tropical EMF involving the right ventricle is presented.
The initial presentation mimicked Ebstein's anomaly, a congenital heart defect.
This diagnostic confusion underscores potential pitfalls in identifying EMF.

Findings:

Accurate differentiation of EMF from conditions like Ebstein's anomaly is crucial.
Right ventricular involvement in EMF can alter its typical presentation.
Timely diagnosis is essential for effective patient management and treatment.

Implications:

Highlights the need for increased awareness of EMF in non-endemic areas.
Emphasizes the importance of considering EMF in patients with unexplained restrictive cardiomyopathy.
Suggests that advanced imaging or diagnostic techniques may be necessary for accurate EMF diagnosis.