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Updated: Oct 26, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
1% Aspiration, 99% Perspiration: Acute Left Atrial Thrombus During Percutaneous Left Atrial Appendage Occlusion
Pankaj Jain1, Neil Jacobs1, David W M Muller1
1Cardiology Department, St. Vincent's Hospital, Sydney, New South Wales, Australia.
Insights
A large thrombus was successfully aspirated during left atrial appendage occlusion in a patient with atrial fibrillation. This intervention prevented complications during the device implantation procedure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Atrial fibrillation increases stroke risk due to potential clot formation in the left atrial appendage.
- Left atrial appendage occlusion (LAAO) devices are used to reduce this risk.
- Complications during LAAO device implantation, such as thrombus formation, require careful management.
Purpose of the Study:
- To describe a case of successful thrombus aspiration during LAAO device implantation.
- To highlight a technique for managing unexpected thrombus during the procedure.
Main Methods:
- A 71-year-old male patient with chronic atrial fibrillation underwent LAAO.
- A large thrombus was identified attached to the delivery system before device release.
- Continuous negative pressure was applied to aspirate the thrombus during device deployment.
Main Results:
- The thrombus was successfully aspirated using the described method.
- The LAAO device was deployed without further complications.
- The patient experienced no clinical sequelae following the procedure.
Conclusions:
- Thrombus aspiration is a feasible technique for managing intraprocedural thrombus during LAAO.
- This approach can ensure successful device implantation and patient safety.
- Careful monitoring and preparedness are crucial for interventional cardiology procedures.
Abstract:
A 71-year-old man with chronic atrial fibrillation underwent insertion of a left atrial appendage occlusion device. Before release, a large thrombus was noted within the left atrium, attached to the left atrial appendage occluder delivery system. With continuous negative pressure, the device was deployed and thrombus successfully aspirated with no clinical sequelae. (Level of Difficulty: Intermediate.).

