Saw-Tooth Cardiomyopathy: Clinical Presentation and Genetic Analysis

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Julie Proukhnitzky1, Jérôme Garot2, Céline Bordet1

  • 1APHP, Département de Génétique & Département de Cardiologie, Centre de Référence des Maladies Cardiaques Héréditaires ou Rares, Hôpital Pitié-Salpêtrière, Paris, France.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

Saw-tooth cardiomyopathy is a rare heart condition. This study details its clinical presentation, imaging, and genetics, distinguishing it from left-ventricular noncompaction.

Area of Science:

  • Cardiology
  • Genetics
  • Medical Imaging

Background:

  • Saw-tooth cardiomyopathy is an exceptionally rare cardiac condition with limited published cases.
  • Distinguishing it from other cardiomyopathies is crucial for accurate diagnosis and management.

Observation:

  • This report details a case of saw-tooth cardiomyopathy.
  • Clinical presentation, cardiac imaging features, and genetic analysis were performed.

Findings:

  • The study presents comprehensive data on a rare saw-tooth cardiomyopathy case.
  • Key imaging and genetic markers are highlighted to differentiate it from left-ventricular noncompaction.

Implications:

  • This research aids in the accurate diagnosis of saw-tooth cardiomyopathy.
  • It provides critical information to prevent misdiagnosis with left-ventricular noncompaction.
  • Understanding saw-tooth cardiomyopathy's unique features is essential for future research and patient care.

Keywords:
ACMG, American College of Medical GeneticsBNP, brain natriuretic peptideCMR, cardiac magnetic resonanceECG, electrocardiogramLV, left ventricleLVNC, left ventricular noncompactioncardiomyopathyleft-ventricular noncompactionmuscular bridgessaw-tooth cardiomyopathyventricular protrusions

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