Related Experiment Video

Updated: Oct 26, 2025

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level
06:02

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level

Published on: November 2, 2020

5.9K

Hypertrophic Cardiomyopathy in Adolescence: Application of Guidelines

Paul F Kantor1, Timothy W Casarez1,2, Yaniv Bar-Cohen1

  • 1Division of Cardiology, Department of Pediatrics, Children's Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

This case study highlights the management of adolescent hypertrophic cardiomyopathy. Early screening and risk stratification are crucial for timely defibrillator implantation in affected individuals.

Area of Science:

  • Cardiology
  • Genetics
  • Adolescent Medicine

Background:

  • Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease often presenting in adolescence.
  • Early identification and management are critical to prevent adverse outcomes.
  • This case focuses on the clinical course and therapeutic strategies for an adolescent male diagnosed with HCM.

Observation:

  • The patient was an adolescent male with a confirmed diagnosis of hypertrophic cardiomyopathy.
  • Key clinical features and diagnostic evaluations were meticulously documented.
  • The importance of a comprehensive family history was underscored in the diagnostic process.

Findings:

  • Accurate evaluation of cardiac hypertrophy is essential for diagnosis and management.
  • Risk stratification is vital for determining eligibility for implantable cardioverter-defibrillators (ICDs).
  • The case illustrates the application of current guidelines in managing HCM.

Implications:

  • Emphasizes the need for early screening protocols in at-risk adolescent populations.
  • Highlights the role of genetic counseling and family history in HCM management.
  • Reinforces the importance of individualized risk assessment for ICD implantation in young patients with HCM.

Keywords:
ECG, electrocardiogramsHCM, hypertrophic cardiomyopathyICD, implantable cardioverter-defibrillatorLV, left ventricularVF, ventricular fibrillationVT, ventricular tachycardiacardiomyopathyventricular fibrillationventricular tachycardia

More Related Videos

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

3.8K
Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice07:55

Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice

Published on: April 7, 2022

3.1K

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
101
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
73
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
87
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
140
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
129
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
83