Heart Block in Unpalliated Complex Adult Congenital Heart Disease: Massive Collateral Burden Precludes Epicardial

Joshua R Hirsch1, Christopher R Broda2, Peter R Ermis2

  • 1Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA.

JACC. Case Reports
|July 28, 2021
PubMed

Insights

Complete heart block in adults with congenital heart disease (CHD) poses challenges. For patients with septal shunting, epicardial pacing is preferred to reduce thromboembolism risk, but complex CHD anatomy can complicate lead placement.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Cardiac Electrophysiology

Background:

  • Complete heart block is a frequent complication in adults with congenital heart disease (CHD).
  • Epicardial pacing is the recommended approach for patients with septal shunting to mitigate thromboembolism risks.
  • Complex anatomical variations in CHD can present challenges for traditional epicardial lead implantation.

Purpose of the Study:

  • To evaluate the efficacy and safety of endocardial pacing in adult CHD patients with complete heart block.
  • To address the challenges of epicardial lead placement in complex CHD anatomy.
  • To investigate the persistent question of thromboembolism risk reduction with endocardial pacing in this specific population.

Main Methods:

  • Review of existing literature on pacing strategies in adult CHD.
  • Analysis of case studies involving complete heart block and complex CHD anatomy.
  • Comparative assessment of thromboembolism risks between epicardial and endocardial pacing in CHD patients.

Main Results:

  • Epicardial pacing is associated with lower thromboembolism risk in CHD patients with septal defects.
  • Anatomical constraints in complex CHD can render surgical epicardial lead placement unfeasible.
  • The effectiveness of endocardial pacing in reducing thromboembolism for these complex CHD cases requires further investigation.

Conclusions:

  • For adult CHD patients with complete heart block and complex anatomy, endocardial pacing may be necessary when epicardial lead placement is not feasible.
  • The management of thromboembolism risk in these patients undergoing endocardial pacing remains an area of concern and requires further research.
  • Optimizing pacing strategies for adult CHD with complete heart block necessitates consideration of both anatomical feasibility and thromboembolic risk.

Related Concept Videos

Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
224
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
101
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
87
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.8K
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
1.7K
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
73