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Eosinophilic Myocarditis in a Patient With Sickle Cell Disease
Hafiz M Imran1,2, Kashif Ather1,2, Ned H Gutman2,3
1Division of Cardiovascular Medicine, Rhode Island Hospital, Providence, Rhode Island, USA.
Abstract:
A 23-year-old man with sickle cell disease treated with splenectomy and allogenic stem cell transplantation presented with recurrent chest pain, elevated cardiac enzymes, and unremarkable electrocardiography. His work-up revealed eosinophilia, raising concern for eosinophilic myocarditis. Cardiac magnetic resonance imaging showed patchy late gadolinium enhancement of the left ventricular free wall, suggestive of myocarditis. He was treated with high-dose intravenous steroids followed by oral prednisone, with improvement in his symptoms and eosinophilia and a decrease in cardiac enhancement on follow-up imaging. (Level of Difficulty: Intermediate.).
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