A 30-Year-Old Man With Primary Cardiac Angiosarcoma

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Nicholas Jex1, Jonathan Farley2, Sharmaine Thirunavukarasu1

  • 1University of Leeds, Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, Leeds, United Kingdom.

JACC. Case Reports
|July 28, 2021
PubMed

Keywords:
CMR, cardiovascular magnetic resonance imagingRA, right atrialRCA, right coronary arteryRV, right ventriclecardiac angiosarcomacardiac magnetic resonanceechocardiographyimagingmalignancypositron emission tomography

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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