Lower urinary tract dysfunction in Parkinsonian syndromes.

Area of Science:

• Neurology
• Urology

Background:

• Lower urinary tract (LUT) dysfunction is a prevalent issue in neurological disorders.
• Parkinsonian syndromes, including Parkinson's disease (PD) and atypical forms like multiple system atrophy (MSA), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD), frequently present with LUT symptoms.

Purpose of the Study:

• To review the clinical presentation, pathophysiology, and evaluation of LUT dysfunction in PD and other parkinsonian syndromes.
• To highlight the variability in LUT dysfunction patterns and severity based on the specific parkinsonian syndrome.

Main Methods:

• This is a review article, synthesizing existing literature.
• The review focuses on clinical presentation, underlying pathophysiology, and diagnostic approaches.

Main Results:

• LUT dysfunction is a common manifestation across various parkinsonian syndromes.
• The specific pattern and severity of LUT dysfunction vary depending on the underlying neurological condition and the location of neural pathway lesions.
• Distinct clinical features of different parkinsonian syndromes correlate with differing LUT dysfunction profiles.

Conclusions:

• Lower urinary tract dysfunction is a significant and common feature in patients with parkinsonian syndromes.
• Identifying characteristic LUT dysfunction patterns during patient assessment can improve management strategies.
• Early recognition of LUT dysfunction may contribute to earlier diagnosis of parkinsonian syndromes.