Biodegradable and Biocompatible 3D Constructs for Dental Applications: Manufacturing Options and Perspectives

Area of Science:

• Biomaterials Engineering
• Dental Regenerative Medicine
• 3D Printing Technology

Background:

• Designing 3D constructs for dental restoration and regeneration is a complex optimization challenge.
• 3D printing is a potent tool for tissue regeneration, but challenges remain in developing suitable inks.
• Current limitations include achieving biocompatibility, biodegradability, stability, and tuneable mechanics in 3D printed dental materials.

Purpose of the Study:

• To review current manufacturing processes for 3D constructs in dentistry.
• To explore methods for creating self-supporting, processable, and cost-effective 3D constructs.
• To highlight the potential of hybrid approaches for advanced dental restorations and implants.

Main Methods:

• Review of existing literature on 3D printing for dental applications.
• Analysis of manufacturing processes for engineered self-supporting constructs.
• Discussion of hybrid synergistic approaches using multi-layered composite building blocks.

Main Results:

• Engineered 3D constructs can be developed with tuneable mechanics, bioactivity, and degradability.
• Hybrid approaches offer optimal solutions for overcoming limitations in current dental materials.
• Composite building blocks with desired physicomechanical performance and bioactivity are achievable.

Conclusions:

• A hybrid synergistic approach using multi-layered composite blocks is optimal for advanced dental applications.
• Further research into manufacturing perspectives can inspire clinical trials for routine dental use.
• 3D printing holds significant potential for revolutionizing dental restorations and implants.