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Synthesis of porphyrin-incorporating covalent organic frameworks for sonodynamic therapy
Sainan Liu1, Ying Zhou, Chunling Hu
1State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, P. R. China. mlpang@ciac.ac.cn.
Chemical Communications (Cambridge, England)
|July 28, 2021
Abstract:
Porphyrin-incorporating covalent organic frameworks were synthesized at room temperature. The resulting products with uniform morphology and excellent crystallinity exhibited good singlet oxygen generation ability. Both in vitro and in vivo experiments demonstrated the significant antitumor efficiency via sonodynamic therapy.
