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Related Experiment Video

Updated: Oct 26, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

Long COVID, a comprehensive systematic scoping review.

Hossein Akbarialiabad¹, Mohammad Hossein Taghrir¹, Ashkan Abdollahi²

¹Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

|July 28, 2021

Summary

This summary is machine-generated.

Long COVID literature shows varied definitions impacting care. Common symptoms include fatigue and breathlessness, with potential long-term organ involvement requiring further study.

Keywords:

COVID-19 Corona virus Long COVID-19 Long haulers COVID Novel Corona Virus 2019 PASC post-acute sequela SARS-COV-2 Post COVID-19 Syndrome Post-acute COVID-19 Post-acute SARS-CoV-2 SARS-Cov-2

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Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

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Published on: September 20, 2024

Area of Science:

Infectious Diseases
Public Health
Medical Literature Review

Background:

Long COVID, a post-viral syndrome following SARS-CoV-2 infection, presents a significant global health challenge.
Understanding the existing body of literature is crucial for developing effective diagnostic and management strategies.

Purpose of the Study:

To conduct a comprehensive scoping review of published literature on Long COVID up to January 30, 2021.
To identify key themes including definition, pathophysiology, symptoms, and management of Long COVID.

Main Methods:

A systematic, four-step literature search was performed across multiple electronic databases with no language restrictions.
Forward and backward citation searching identified additional relevant publications.
PRISMA-ScR guidelines were followed for this scoping review, including translation of non-English articles.

Main Results:

The review analyzed 120 publications, predominantly observational studies (22 cohort, 28 cross-sectional), with only one randomized clinical trial.
Key research areas included signs and symptoms (49.1%), management (23.3%), and pathophysiology (10.8%).
Narrative synthesis covered nomenclature, diagnosis, pathophysiology, risk factors, signs/symptoms, and management.

Conclusions:

Ambiguity in Long COVID definitions hinders recognition and clinical management.
Predominant symptoms reported are fatigue, dyspnea, arthralgia, sleep disturbances, and chest pain.
Emerging evidence suggests potential long-term sequelae affecting multiple organ systems (cutaneous, respiratory, cardiovascular, musculoskeletal, neurological, renal, mental health).