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Accommodative response to ocular surface pain.

Emmanuel B Alabi¹, Trefford L Simpson¹

¹School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.

Clinical & Experimental Optometry

|July 28, 2021

Summary

This summary is machine-generated.

Noxious corneal stimulation increases eye accommodation in a dose-dependent manner. This ocular surface response, unlike pupil response, may indicate underlying discomfort and warrants clinical attention.

Keywords:

Accommodation Corneal pain Pupil response esthesiometer

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Area of Science:

Ophthalmology
Neuroscience
Physiology

Background:

No prior studies have investigated the impact of noxious stimulation on the eye's accommodative system.
This research characterizes the accommodative response to corneal stimulation in healthy individuals.

Purpose of the Study:

To investigate the relationship between noxious corneal stimulation and the accommodative response.
To determine if stimulus intensity or modality affects accommodation and pupil size.

Main Methods:

A pneumatic esthesiometer delivered mechanical and chemical stimuli to the cornea of 15 healthy subjects.
Accommodative and pupil responses were measured using infrared photorefraction.
Repeated measures ANOVA analyzed quantitative differences in responses.

Main Results:

Accommodation significantly increased with rising stimulus intensity, regardless of modality (p < 0.05).
The highest stimulus level (200% threshold) elicited a greater accommodative response than lower levels (p < 0.05).
Pupil responses did not vary significantly with stimulus intensity, and no significant differences were found between eyes.

Conclusions:

Noxious corneal stimulation induces a dose-dependent increase in ocular accommodation.
The pupil response does not appear to be dose-dependent on corneal stimulation.
Findings suggest ocular discomfort may influence visual optical effects, potentially requiring accommodative system assessment.