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Published on: September 24, 2020
Hospitalization, Mechanical Ventilation, and Mortality After COVID-19 Among Adults With or Without Serious Mental
Karly A Murphy1, Emma E McGinty1, Gail L Daumit1
1Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore (Murphy, Daumit); Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore (Murphy); Department of Health Policy and Management (McGinty), and Department of Mental Health (McGinty, Daumit), Johns Hopkins Bloomberg School of Public Health, Baltimore.
Objective:
The authors evaluated the likelihood of hospital admission, mechanical ventilation, and mortality within 30 days after a COVID-19 diagnosis among persons with or without serious mental illness.
Methods:
Adults with and without serious mental illness diagnosed as having COVID-19 in the first year of the pandemic were identified in the TriNetX database, a network of electronic health records from 49 U.S. health care systems representing 63.5 million individuals. A propensity score approach was used to compare outcomes of unmatched and matched cohorts (N=85,257).
Results:
Compared with persons without serious mental illness, persons with serious mental illness were more likely to be hospitalized or to die after COVID-19 diagnosis. No difference in mortality or use of mechanical ventilation was observed among groups admitted to the hospital with COVID-19.
Conclusions:
Disparities in overall mortality after COVID-19 for persons with serious mental illness likely were driven by factors outside of acute care settings.
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